Are polynucleotides safe and natural? Have you ever looked in the mirror and felt like your skin looked… tired? Not just in need of a glow-up, but like it had lost its bounce, its smoothness, its spark? If you’ve been searching for something that nurtures your skin instead of just masking the signs of ageing, chances are you’ve come across polynucleotides. And rightly so. Let’s address your biggest question first: Yes, polynucleotides are both safe and natural. They’re derived from purified DNA fragments, most often from salmon, because their molecular structure is remarkably similar to human DNA. They’re biocompatible, meaning your skin recognises them, welcomes them, and begins to regenerate from the inside out. Used by dermatologists and aesthetic clinics worldwide, polynucleotides have been studied extensively and are proven to be non-toxic, non-inflammatory, and highly effective at repairing, healing, and rejuvenating skin, without altering your natural features.
What makes polynucleotides so unique?
Think of them as the architects of cellular renewal. While fillers work by adding volume, and traditional skin boosters hydrate the skin’s surface, polynucleotides go deeper. They stimulate tissue repair, calm inflammation, and trigger fibroblasts to produce more collagen and elastin, giving your skin a naturally firmer, smoother, and more radiant appearance.
This isn’t about chasing perfection. It’s about choosing a science-backed, skin-loving option that supports your skin health through every decade of life.
And if you’re wondering – Are polynucleotides safe and natural?
The answer is still yes. Polynucleotides are not synthetic. They come from natural DNA sources (usually salmon sperm) that are purified, filtered, and refined until they’re safe for human use. Nothing artificial. Nothing unnecessary.
Who are polynucleotides for and what can you expect?
- In your 30s? You’ll love how it revives tired skin and prevents early ageing.
- In your 40s and 50s? It softens lines, restores density, and renews skin from within.
- Struggling with pigmentation, scarring, or sensitivity? Polynucleotides soothe, correct, and rebuild, making them ideal for compromised or fragile skin that hasn’t responded well to other treatments.
Even better, they pair beautifully with other aesthetic procedures like microneedling or laser. So if you’ve already had Botox or fillers, think of polynucleotides as your skin’s repair system, quietly working in the background, restoring strength and resilience.
Why trust matters more than ever?
In an industry full of trends and quick fixes, it’s easy to feel overwhelmed. But your skin deserves more than guesswork.
At Skin Perfection London, we specialise in advanced skin boosters like polynucleotides. Every treatment is tailored to your skin’s unique needs, not just its surface concerns, but its deeper structure and long-term health.
Want to find out if Polynucleotides are right for you?
Book a free skin consultation at our London clinic. You’ll receive a full skin analysis, expert advice, and a bespoke treatment plan designed around your skin’s real needs, so you can make confident, informed decisions about your skin’s future.







